PMID:14630323
| Citation |
Stroud, RM, Savage, D, Miercke, LJ, Lee, JK, Khademi, S and Harries, W (2003) Selectivity and conductance among the glycerol and water conducting aquaporin family of channels. FEBS Lett. 555:79-84 |
|---|---|
| Abstract |
The atomic structures of a transmembrane water plus glycerol conducting channel (GlpF), and now of aquaporin Z (AqpZ) from the same species, Escherichia coli, bring the total to three atomic resolution structures in the aquaporin (AQP) family. Members of the AQP family each assemble as tetramers of four channels. Common helical axes support a wider channel in the glycerol plus water channel paradigm, GlpF. Water molecules form a single hydrogen bonded file throughout the 28 A long channel in AqpZ. The basis for absolute exclusion of proton or hydronium ion conductance through the line of water is explored using simulations. |
| Links | |
| Keywords |
Amino Acid Sequence; Aquaporin 1; Aquaporins/chemistry; Aquaporins/genetics; Aquaporins/metabolism; Carbohydrate Metabolism; Electric Conductivity; Electrochemistry; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Duplication; Glycerol/metabolism; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Potassium Channels/chemistry; Protein Conformation; Sequence Homology, Amino Acid; Water/metabolism |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.