PMID:14607068

Citation	Tendeng, C and Bertin, PN (2003) H-NS in Gram-negative bacteria: a family of multifaceted proteins. Trends Microbiol. 11:511-8
Abstract	DNA-packaging and the control of gene expression constitute a major challenge for bacteria to survive and adapt to environmental changes. The use of multiple strategies to solve these problems could explain the presence of various nucleoid-associated proteins in bacteria. H-NS, one of these proteins, has been extensively studied in Escherichia coli, and a variety of phenotypes have been associated with a mutation in its structural gene. However, the role of H-NS in bacterial physiology and its mechanism of action are still a matter of debate. The expanding number of H-NS-related proteins identified in Gram-negative bacteria reveals interesting clues about their structure-function-evolution relationship.
Links	PubMed
Keywords	Bacterial Proteins/genetics; Bacterial Proteins/isolation & purification; Bacterial Proteins/physiology; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/classification; DNA-Binding Proteins/genetics; DNA-Binding Proteins/isolation & purification; DNA-Binding Proteins/physiology; Evolution, Molecular; Forecasting; Gram-Negative Bacteria/genetics; Gram-Negative Bacteria/physiology
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