PMID:14565453

Citation	Taranenko, MV, Sumbatyan, NV, Mtchedlidze, MT and Kuznetsova, SA Cross-linking of Escherichia coli formamidopyrymidine-DNA glycosylase to DNA duplexes containing photoactivatable phenyl(trifluoromethyl)diazirine groups. Nucleosides Nucleotides Nucleic Acids 22:1505-7
Abstract	New reactive analogs of substrates for DNA repair enzyme E. coli Fpg protein containing the residues of 8-oxoguanine and photoactivatable phenyl(trifluoromethyl)diazirine groups were synthesized. Their substrate properties were investigated. Using photocross-linking technique, we established the presence of contacts of two nucleosides located near the oxoG with amino acids from the Fpg protein. The cross-linking efficiency achieved 10%.
Links	PubMed Online version:10.1081/NCN-120023021
Keywords	Base Sequence; Cross-Linking Reagents; DNA/chemistry; DNA/metabolism; DNA-Formamidopyrimidine Glycosylase/metabolism; Diazomethane; Escherichia coli/enzymology; Oligodeoxyribonucleotides/chemistry; Oligodeoxyribonucleotides/metabolism
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