PMID:14507478

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Citation

Kuhn, A, Stuart, R, Henry, R and Dalbey, RE (2003) The Alb3/Oxa1/YidC protein family: membrane-localized chaperones facilitating membrane protein insertion? Trends Cell Biol. 13:510-6

Abstract

The recently identified Alb3/Oxa1/YidC family constitutes a novel class of proteins that function in promoting membrane insertion in chloroplasts, mitochondria and bacteria. These proteins mediate membrane insertion of a diverse group of membrane proteins that range from phage coat proteins in bacteria and respiratory-chain protein subunits in mitochondria to the light-harvesting chlorophyll-binding proteins in chloroplasts. Here, we discuss the Alb3/Oxa1/YidC protein family and their possible function as membrane chaperones, helping newly synthesized proteins to fold into the membrane bilayer.

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Keywords

Arabidopsis Proteins/chemistry; Arabidopsis Proteins/metabolism; Electron Transport Complex IV; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/metabolism; Membrane Proteins/metabolism; Membrane Transport Proteins/chemistry; Membrane Transport Proteins/metabolism; Mitochondrial Proteins; Molecular Chaperones/chemistry; Molecular Chaperones/metabolism; Nuclear Proteins/chemistry; Nuclear Proteins/metabolism

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