PMID:14506846

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Citation

Daraselia, N, Dernovoy, D, Tian, Y, Borodovsky, M, Tatusov, R and Tatusova, T (2003) Reannotation of Shewanella oneidensis genome. OMICS 7:171-5

Abstract

As more and more complete bacterial genome sequences become available, the genome annotation of previously sequenced genomes may become quickly outdated. This is primarily due to the discovery and functional characterization of new genes. We have reannotated the recently published genome of Shewanella oneidensis with the following results: 51 new genes have been identified, and functional annotation has been added to the 97 genes, including 15 new and 82 existing ones with previously unassigned function. The identification of new genes was achieved by predicting the protein coding regions using the HMM-based program GeneMark.hmm. Subsequent comparison of the predicted gene products to the non-redundant protein database using BLAST and the COG (Clusters of Orthologous Groups) database using COGNITOR provided for the functional annotation.

Links

PubMed Online version:10.1089/153623103322246566

Keywords

Algorithms; Bacterial Proteins/genetics; Bacterial Proteins/physiology; Computational Biology/methods; Genes, Bacterial/genetics; Genome, Bacterial; Genomics; Molecular Sequence Data; Open Reading Frames/genetics; Sequence Alignment/methods; Shewanella/genetics; Software

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