PMID:1447156

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Citation

Sharma, B and Hill, TM (1992) TerF, the sixth identified replication arrest site in Escherichia coli, is located within the rcsC gene. J. Bacteriol. 174:7854-8

Abstract

We report the existence of a sixth replication arrest site, TerF, that is located within the coding sequences of the rcsC gene, a negative regulator of capsule biosynthesis. The TerF site is oriented to allow transcription of the rcsC gene but prevent DNA replication in the terminus-to-origin direction. Our results demonstrate that the TerF site is functional in both chromosomal and plasmid environments and that the stability of the Tus-TerF protein-DNA complex more closely resembles the plasmid R6K Ter sites than the chromosomal TerB site.

Links

PubMed PMC207506

Keywords

Bacterial Proteins/genetics; Base Sequence; Chromosome Mapping; DNA Replication; Escherichia coli/genetics; Escherichia coli Proteins; Genes, Bacterial/genetics; Genes, Regulator/genetics; Molecular Sequence Data; Multienzyme Complexes; Phosphoprotein Phosphatases; Plasmids/genetics; Protein Kinases; Regulatory Sequences, Nucleic Acid/genetics; Transcription Factors/genetics

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