PMID:1370545
| Citation |
Li, WQ and Yarus, M (1992) Bar to normal UGA translation by the selenocysteine tRNA. J. Mol. Biol. 223:9-15 |
|---|---|
| Abstract |
The selC gene product, tRNA(Sec), inserts selenocysteine at UGA (opal) codons in a specialized mRNA context. We have investigated the action of the tRNA at ordinary UGA codons, normally not translated, by changing the unusual structural features of tRNA(Sec). Sequences in the D arm, CCA arm and variable arm of the tRNA all contribute to the prohibition against translation of ordinary UGA codons. One multiple mutant is a moderately efficient serine-inserting UGA suppressor tRNA. |
| Links | |
| Keywords |
Base Sequence; Codon; DNA, Bacterial/genetics; Escherichia coli/genetics; Genes, Suppressor; Molecular Sequence Data; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Bacterial/metabolism; RNA, Messenger/metabolism; RNA, Transfer, Amino Acid-Specific/genetics |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.