PMID:1310504

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Citation

Ikeda, TP, Houtz, E and LaPorte, DC (1992) Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity. J. Bacteriol. 174:1414-6

Abstract

Mutations in aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase, which selectively inhibit phosphatase activity have been isolated. These mutations yield amino acid substitutions within a 113-residue region of this 578-residue protein. These mutations may define a regulatory domain of this protein.

Links

PubMed PMC206440

Keywords

DNA Mutational Analysis; Escherichia coli/enzymology; Escherichia coli/genetics; Mutation/genetics; Phosphoprotein Phosphatases/genetics; Phosphoprotein Phosphatases/metabolism; Protein Kinases/genetics; Protein Kinases/metabolism; Protein-Serine-Threonine Kinases; Transformation, Bacterial/genetics

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