PMID:12952533
| Citation |
Reed, JL, Vo, TD, Schilling, CH and Palsson, BO (2003) An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Genome Biol. 4:R54 |
|---|---|
| Abstract |
Diverse datasets, including genomic, transcriptomic, proteomic and metabolomic data, are becoming readily available for specific organisms. There is currently a need to integrate these datasets within an in silico modeling framework. Constraint-based models of Escherichia coli K-12 MG1655 have been developed and used to study the bacterium's metabolism and phenotypic behavior. The most comprehensive E. coli model to date (E. coli iJE660a GSM) accounts for 660 genes and includes 627 unique biochemical reactions. |
| Links |
PubMed PMC193654 Online version:10.1186/gb-2003-4-9-r54 |
| Keywords |
Citric Acid Cycle/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Genes, Bacterial/genetics; Genome, Bacterial; Glycerol/metabolism; Ketoglutaric Acids/metabolism; Models, Biological; Open Reading Frames/genetics |
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