PMID:12906810
| Citation |
Davey, MJ and O'Donnell, M (2003) Replicative helicase loaders: ring breakers and ring makers. Curr. Biol. 13:R594-6 |
|---|---|
| Abstract |
Helicase loaders transfer the ring-shaped replicative helicases onto DNA. They assort into two classes: ring breakers, which place stabile hexameric rings on DNA via transient gaps at subunit interfaces; and helicase makers, which assemble hexameric rings around DNA from monomeric helicase units. |
| Links | |
| Keywords |
DNA/metabolism; DNA Helicases/metabolism; DNA Replication/genetics; Escherichia coli Proteins/metabolism; Models, Molecular |
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