PMID:12813093
| Citation |
McKenzie, GJ, Magner, DB, Lee, PL and Rosenberg, SM (2003) The dinB operon and spontaneous mutation in Escherichia coli. J. Bacteriol. 185:3972-7 |
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| Abstract |
Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB-yafN-yafO-yafP. The results imply a role for yafN, yafO, and/or yafP in spontaneous mutation. |
| Links | |
| Keywords |
Alleles; Bacterial Proteins/genetics; DNA Polymerase beta; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Expression Regulation, Bacterial; Mutation; Operon; SOS Response (Genetics) |
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