PMID:12795410
| Citation |
Slavcev, RA, Bull, HJ and Hayes, S (2003) Bacteriophage lambda repressor allelic modulation of the Rex exclusion phenotype. Can. J. Microbiol. 49:225-9 |
|---|---|
| Abstract |
The sensitivity of delta red-gam delta ren mutants of bacteriophage lambda to Rex exclusion by lambda rexA+ rexB+ lysogens is modulated by the prophage cI repressor allele. We show the following: (i) lambda spi156 delta nin5 forms plaques on a cI+-rexA+-rexB+ lysogen with 10(5)-fold higher efficiency than on cI[Ts]-rexA+-rexB+ derivatives. (ii) The cI[Ts]857 allele augmentation of Rex exclusion is recessive to cI+. (iii) The cI857-mediated increase in Rex exclusion activity involves the participation of a genetic element mapping outside of cI-rexA-rexB. |
| Links |
PubMed Online version:10.1139/w03-021 |
| Keywords |
Alleles; Bacteriophage lambda/genetics; DNA-Binding Proteins; Escherichia coli/genetics; Genes, Viral; Models, Genetic; Phenotype; Plasmids/analysis; Repressor Proteins/genetics; Repressor Proteins/metabolism; Viral Nonstructural Proteins/genetics; Viral Proteins/genetics; Viral Regulatory and Accessory Proteins |
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