PMID:12783628

Citation	Larsen, TS and Krogh, A (2003) EasyGene--a prokaryotic gene finder that ranks ORFs by statistical significance. BMC Bioinformatics 4:21
Abstract	Contrary to other areas of sequence analysis, a measure of statistical significance of a putative gene has not been devised to help in discriminating real genes from the masses of random Open Reading Frames (ORFs) in prokaryotic genomes. Therefore, many genomes have too many short ORFs annotated as genes.
Links	PubMed PMC521197 Online version:10.1186/1471-2105-4-21
Keywords	Bacillus subtilis/genetics; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Binding Sites/genetics; Computational Biology/methods; Computational Biology/statistics & numerical data; Escherichia coli/genetics; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Genes, Bacterial/genetics; Genome, Bacterial; Helicobacter pylori/genetics; Markov Chains; Models, Genetic; Models, Statistical; Mycobacterium tuberculosis/genetics; Open Reading Frames/genetics; Predictive Value of Tests; Ribosomes/chemistry; Ribosomes/genetics; Sensitivity and Specificity
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