PMID:12718870
| Citation |
de la Cueva-Méndez, G (2003) Distressing bacteria: structure of a prokaryotic detox program. Mol. Cell 11:848-50 |
|---|---|
| Abstract |
MazF and MazE are components of a chromosomal toxin-antitoxin system of Escherichia coli. In this issue of Molecular Cell, Kamada et al. describe the crystal structure of a MazE/MazF heterohexamer and propose that the mechanism of toxin-antidote recognition is common to other homologous chromosomal and plasmid-borne systems. |
| Links | |
| Keywords |
Antitoxins/biosynthesis; Antitoxins/genetics; Bacterial Toxins/genetics; Bacterial Toxins/metabolism; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Endoribonucleases; Escherichia coli/metabolism; Escherichia coli Proteins; Plasmids/genetics; Plasmids/metabolism; Prokaryotic Cells/metabolism |
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