PMID:12702811
| Citation |
Li, Y, Cole, K and Altman, S (2003) The effect of a single, temperature-sensitive mutation on global gene expression in Escherichia coli. RNA 9:518-32 |
|---|---|
| Abstract |
High-density DNA microarrays have been used to explore the genomic profiling of gene expression of a defective Escherichia coli strain with a temperature-sensitive mutation in the protein component of RNase P. A novel gene cluster was discovered in which two of the genes are known substrates of RNase P. The expression pattern of essential genes and gene discovery from intergenic regions, for which other new transcripts are found, are also discussed. |
| Links | |
| Keywords |
Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Endoribonucleases/genetics; Endoribonucleases/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Profiling; Genes, Bacterial; Multigene Family; Oligonucleotide Array Sequence Analysis; Point Mutation; RNA, Catalytic/genetics; RNA, Catalytic/metabolism; Ribonuclease P; Substrate Specificity; Temperature |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.