PMID:12670992

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Citation

Nishino, K, Inazumi, Y and Yamaguchi, A (2003) Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli. J. Bacteriol. 185:2667-72

Abstract

The response regulator EvgA controls expression of multiple genes conferring antibiotic resistance in Escherichia coli (K. Nishino and A. Yamaguchi, J. Bacteriol. 184:2319-2323, 2002). To understand the whole picture of EvgA regulation, DNA macroarray analysis of the effect of EvgA overproduction was performed. EvgA activated genes related to acid resistance, osmotic adaptation, and drug resistance.

Links

PubMed PMC152604

Keywords

Acids; Adaptation, Physiological; Bacterial Proteins/metabolism; Drug Resistance, Bacterial; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; Osmolar Concentration; Signal Transduction; Transcription Factors/metabolism

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