PMID:12620121

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Citation

Anantharaman, V and Aravind, L (2003) Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol. 4:R11

Abstract

Peptidoglycan is hydrolyzed by a diverse set of enzymes during bacterial growth, development and cell division. The N1pC/P60 proteins define a family of cell-wall peptidases that are widely represented in various bacterial lineages. Currently characterized members are known to hydrolyze D-gamma-glutamyl-meso-diaminopimelate or N-acetylmuramate-L-alanine linkages.

Links

PubMed PMC151301

Keywords

Amino Acid Sequence; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Evolution, Molecular; Models, Molecular; Molecular Sequence Data; Multigene Family/genetics; Peptide Hydrolases/chemistry; Peptide Hydrolases/genetics; Peptide Hydrolases/metabolism; Phylogeny; Sequence Alignment; Sequence Homology, Amino Acid

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