PMID:12590654
| Citation |
Iyer, LM, Anantharaman, V and Aravind, L (2003) Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins. BMC Genomics 4:5 |
|---|---|
| Abstract |
Soluble guanylyl cyclases (SGCs) are dimeric enzymes that transduce signals downstream of nitric oxide (NO) in animals. They sense NO by means of a heme moiety that is bound to their N-terminal extensions. |
| Links | |
| Keywords |
Animals; Bacterial Proteins/genetics; Binding Sites; Conserved Sequence; Dimerization; Guanylate Cyclase/genetics; Guanylate Cyclase/metabolism; Heme/metabolism; Nitric Oxide/metabolism |
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