PMID:12443537
| Citation |
de Visser, JA and Lenski, RE (2002) Long-term experimental evolution in Escherichia coli. XI. Rejection of non-transitive interactions as cause of declining rate of adaptation. BMC Evol. Biol. 2:19 |
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| Abstract |
Experimental populations of Escherichia coli have evolved for 20,000 generations in a uniform environment. Their rate of improvement, as measured in competitions with the ancestor in that environment, has declined substantially over this period. This deceleration has been interpreted as the bacteria approaching a peak or plateau in a fitness landscape. Alternatively, this deceleration might be caused by non-transitive competitive interactions, in particular such that the measured advantage of later genotypes relative to earlier ones would be greater if they competed directly. |
| Links | |
| Keywords |
Adaptation, Physiological/genetics; Analysis of Variance; Escherichia coli/genetics; Escherichia coli/physiology; Evolution, Molecular; Genotype; Models, Biological; Selection, Genetic |
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