PMID:12423782
| Citation |
Lazzaroni, JC, Dubuisson, JF and Vianney, A The Tol proteins of Escherichia coli and their involvement in the translocation of group A colicins. Biochimie 84:391-7 |
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| Abstract |
The Tol proteins are involved in outer membrane stability of Gram-negative bacteria. The TolQRA proteins form a complex in the inner membrane while TolB and Pal interact near the outer membrane. These two complexes are transiently connected by an energy-dependent interaction between Pal and TolA. The Tol proteins have been parasitized by group A colicins for their translocation through the cell envelope. Recent advances in the structure and energetics of the Tol system, as well as the interactions between the N-terminal translocation domain of colicins and the Tol proteins are presented. |
| Links | |
| Keywords |
Colicins/metabolism; Escherichia coli/metabolism; Escherichia coli Proteins/metabolism; Membrane Proteins/metabolism; Protein Transport/physiology |
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