PMID:12218041
| Citation |
Merlin, C, Gardiner, G, Durand, S and Masters, M (2002) The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). J. Bacteriol. 184:5513-7 |
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| Abstract |
We report that the genes abc, yaeC, and yaeE comprise metD, an Escherichia coli locus encoding a DL-methionine uptake system. MetD is an ABC transporter with Abc the ATPase, YaeE the permease, and YaeC the likely substrate binding protein. Expression of these genes is regulated by L-methionine and MetJ, a common repressor of the methionine regulon. We propose to rename abc, yaeE, and yaeC as metN, metI, and metQ, respectively. |
| Links | |
| Keywords |
ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Adenosine Triphosphatases/genetics; Adenosine Triphosphatases/metabolism; Amino Acid Transport Systems/genetics; Amino Acid Transport Systems/metabolism; Carrier Proteins/genetics; Carrier Proteins/metabolism; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Deletion; Gene Expression Regulation, Bacterial; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Methionine/metabolism; Molecular Sequence Data; Multigene Family; Transcription, Genetic |
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