PMID:12218038
| Citation |
Jordan, SW and Cronan, JE Jr (2002) Chromosomal amplification of the Escherichia coli lipB region confers high-level resistance to selenolipoic acid. J. Bacteriol. 184:5495-501 |
|---|---|
| Abstract |
One of the mutants (slr7 mutant) of a wild-type Escherichia coli strain resistant to selenolipoic acid reported previously (K. E. Reed, T. W. Morris, and J. E. Cronan, Jr., Proc. Natl. Acad. Sci. USA 91:3720-3724, 1994) unexpectedly grew on minimal medium following transductional introduction of a lipA null mutation. We report that the slr7 strain carries a duplication of the lip chromosomal region that causes the phenotype of the mutant strain. |
| Links | |
| Keywords |
Acyltransferases; Antioxidants/pharmacology; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Blotting, Southern; Chromosomes, Bacterial; Drug Resistance, Bacterial; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli Proteins; Mutation; Plasmids; Proteins/genetics; Recombination, Genetic; Selenium/chemistry; Selenium/pharmacology; Thioctic Acid/pharmacology; Transduction, Genetic |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.