PMID:12169553

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Citation

Ong, IM, Glasner, JD and Page, D (2002) Modelling regulatory pathways in E. coli from time series expression profiles. Bioinformatics 18 Suppl 1:S241-8

Abstract

Cells continuously reprogram their gene expression network as they move through the cell cycle or sense changes in their environment. In order to understand the regulation of cells, time series expression profiles provide a more complete picture than single time point expression profiles. Few analysis techniques, however, are well suited to modelling such time series data.

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Keywords

Adaptation, Physiological/physiology; Bayes Theorem; Escherichia coli/physiology; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Expression Profiling/methods; Gene Expression Regulation, Bacterial/physiology; Models, Biological; Models, Statistical; Signal Transduction/physiology; Time Factors

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