PMID:12150901

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Citation

Woolford, J (2002) Chaperoning ribosome assembly. Mol. Cell 10:8-10

Abstract

Reconstitution of bacterial ribosomes in vitro from RNA and protein constituents requires a heating step to rearrange conformation of an intermediate. In this issue of Molecular Cell, Maki et al. demonstrate that the DnaK chaperone system circumvents the requirement for heating.

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Keywords

Escherichia coli Proteins/metabolism; HSP70 Heat-Shock Proteins/metabolism; Hot Temperature; RNA, Bacterial/metabolism; Ribosomal Proteins/metabolism; Ribosomes/chemistry; Ribosomes/metabolism

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