PMID:12147514

Citation	Morohoshi, T, Maruo, T, Shirai, Y, Kato, J, Ikeda, T, Takiguchi, N, Ohtake, H and Kuroda, A (2002) Accumulation of inorganic polyphosphate in phoU mutants of Escherichia coli and Synechocystis sp. strain PCC6803. Appl. Environ. Microbiol. 68:4107-10
Abstract	The biological process for phosphate (P(i)) removal is based on the use of bacteria capable of accumulating inorganic polyphosphate (polyP). We obtained Escherichia coli mutants which accumulate a large amount of polyP. The polyP accumulation in these mutants was ascribed to a mutation of the phoU gene that encodes a negative regulator of the P(i) regulon. Insertional inactivation of the phoU gene also elevated the intracellular level of polyP in Synechocystis sp. strain PCC6803. The mutant could remove fourfold more P(i) from the medium than the wild-type strain removed.
Links	PubMed PMC124021
Keywords	Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Culture Media; Cyanobacteria/genetics; Cyanobacteria/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Mutation; Phosphates/metabolism; Polyphosphates/metabolism; Regulon; Transcription Factors
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