PMID:12121720
| Citation |
Cronan, JE Jr and Waldrop, GL (2002) Multi-subunit acetyl-CoA carboxylases. Prog. Lipid Res. 41:407-35 |
|---|---|
| Abstract |
Acetyl-CoA carboxylase (ACC) catalyses the first committed step of fatty acid synthesis, the carboxylation of acetyl-CoA to malonyl-CoA. Two physically distinct types of enzymes are found in nature. Bacterial and most plant chloroplasts contain a multi-subunit ACC (MS-ACC) enzyme that is readily dissociated into its component proteins. Mammals, fungi, and plant cytosols contain the second type of ACC, a single large multifunctional polypeptide. This review will focus on the structures, regulation, and enzymatic mechanisms of the bacterial and plant MS-ACCs. |
| Links | |
| Keywords |
Acetyl-CoA Carboxylase/chemistry; Acetyl-CoA Carboxylase/genetics; Acetyl-CoA Carboxylase/physiology; Carrier Proteins/chemistry; Catalysis; Escherichia coli/enzymology; Fatty Acid Synthetase Complex, Type II; Humans; Mutation; Plants/enzymology; Structure-Activity Relationship |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.