PMID:12079504

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Citation

Bearson, SM, Albrecht, JA and Gunsalus, RP (2002) Oxygen and nitrate-dependent regulation of dmsABC operon expression in Escherichia coli: sites for Fnr and NarL protein interactions. BMC Microbiol. 2:13

Abstract

Escherichia coli, can respire anaerobically using dimethyl sulfoxide (DMSO) or trimethylamine-N-oxide (TMAO) as the terminal electron acceptor for anaerobic energy generation. Expression of the dmsABC genes that encode the membrane-associated DMSO/TMAO reductase is positively regulated during anaerobic conditions by the Fnr protein and negatively regulated by the NarL protein when nitrate is present.

Links

PubMed PMC116602

Keywords

Aerobiosis/physiology; Bacterial Proteins/metabolism; Binding Sites/genetics; Binding Sites/physiology; DNA, Bacterial/genetics; DNA, Bacterial/metabolism; DNA-Binding Proteins/metabolism; Escherichia coli/enzymology; Escherichia coli Proteins/physiology; Gene Expression Regulation, Bacterial/physiology; Gene Expression Regulation, Enzymologic/physiology; Iron-Sulfur Proteins/metabolism; Iron-Sulfur Proteins/physiology; Lac Operon/genetics; Molybdenum/metabolism; Nitrates/physiology; Operon/genetics; Operon/physiology; Oxidoreductases/chemistry; Oxidoreductases/genetics; Oxygen/physiology; Promoter Regions, Genetic/genetics; Promoter Regions, Genetic/physiology; Recombinant Fusion Proteins/biosynthesis; Recombinant Fusion Proteins/genetics; Transcription Factors/metabolism

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