PMID:12019019
| Citation |
Jin, J, Gao, P and Mao, Y (2002) Occurrence of leu+ revertants under starvation cultures in Escherichia coli is growth-dependent. BMC Genet. 3:6 |
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| Abstract |
Many investigations have reported that advantageous mutations occurred more frequently under selective conditions than those under non-selective conditions. This phenomenon is referred to as adaptive mutation. Their characteristics are that adaptive mutations are directed and growth-independent. The idea of directed adaptive mutation had been objected by some reports, however, the idea of growth-independent adaptive mutation has been held till today. |
| Links | |
| Keywords |
3-Isopropylmalate Dehydrogenase; Adaptation, Physiological/genetics; Alcohol Oxidoreductases/genetics; Cell Count; Cell Division; Culture Media/chemistry; Culture Media/metabolism; DNA, Bacterial/genetics; Escherichia coli/cytology; Escherichia coli/enzymology; Escherichia coli/growth & development; Escherichia coli/metabolism; Genes, Bacterial/physiology; Leucine/biosynthesis; Leucine/metabolism; Mutagenesis/genetics; Mutation/genetics; Sequence Analysis, DNA |
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