PMID:11958996
| Citation |
Vincent, S, Chen, S, Wilson, DB and Ganem, B (2002) Probing the overlap of chorismate mutase and prephenate dehydrogenase sites in the escherichia coli T-protein: a dehydrogenase-selective inhibitor. Bioorg. Med. Chem. Lett. 12:929-31 |
|---|---|
| Abstract |
An inhibitor of prephenate dehydrogenase has been identified that has no effect on the chorismate mutase activity in the Escherichia coli T-protein, thus supporting the idea of two separate active sites. |
| Links | |
| Keywords |
Binding Sites; Chorismate Mutase/drug effects; Chorismate Mutase/metabolism; Enzyme Inhibitors; Escherichia coli/chemistry; Kinetics; Prephenate Dehydrogenase/antagonists & inhibitors; Structure-Activity Relationship |
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