PMID:11948170
| Citation |
Chung, YJ and Saier, MH Jr (2002) Overexpression of the Escherichia coli sugE gene confers resistance to a narrow range of quaternary ammonium compounds. J. Bacteriol. 184:2543-5 |
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| Abstract |
SugE of Escherichia coli, first identified as a suppressor of groEL mutations but a member of the small multidrug resistance family, has not previously been shown to confer a drug resistance phenotype. We show that high-level expression of sugE leads to resistance to a subset of toxic quaternary ammonium compounds. |
| Links | |
| Keywords |
Bacterial Proteins/metabolism; Drug Resistance, Bacterial; Escherichia coli/drug effects; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Regulation, Bacterial/drug effects; Membrane Proteins; Microbial Sensitivity Tests; Molecular Chaperones; Quaternary Ammonium Compounds/pharmacology |
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