PMID:11914367
| Citation |
Nishino, K and Yamaguchi, A (2002) EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli. J. Bacteriol. 184:2319-23 |
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| Abstract |
Overexpression of the EvgA regulator of the two-component signal transduction system was previously found to modulate multidrug resistance of Escherichia coli by increasing efflux of drugs (K. Nishino and A. Yamaguchi, J. Bacteriol. 183:1455-1458, 2001). Here we present data showing that EvgA contributes to multidrug resistance through increased expression of the multidrug transporter yhiUV gene. |
| Links | |
| Keywords |
Bacterial Outer Membrane Proteins/physiology; Bacterial Proteins/physiology; Base Sequence; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Genes, Bacterial; Genes, MDR; Genes, Regulator; Membrane Transport Proteins; Molecular Sequence Data; Phosphorylation; Polymerase Chain Reaction; Promoter Regions, Genetic; Signal Transduction; Transcription Factors/physiology |
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