PMID:11881892

Citation	Kranz, RG, Beckett, CS and Goldman, BS Genomic analyses of bacterial respiratory and cytochrome c assembly systems: Bordetella as a model for the system II cytochrome c biogenesis pathway. Res. Microbiol. 153:1-6
Abstract	An analysis of thirty-three genomes of selected bacteria for the presence of specific respiratory pathways and cytochrome c biogenesis systems has led to observations on respiration and biogenesis. A table summarizing these results is presented. The data suggested that Bordetella pertussis would be an excellent genetic model to study the System II cytochrome c biogenesis pathway. These observations are discussed and the results of genetic studies on System II biogenesis in B. pertussis are presented as a case for the power of comparative genomics. System II is present in organisms as diverse as Helicobacter, Neisseria, Porphyromonas, mycobacteria, cyanobacteria, and plants (chloroplasts), indicating this pathway's prominence and that horizontal transfer of system II (and/or System I) must have occurred on multiple occasions.
Links	PubMed
Keywords	Bacteria/enzymology; Bacteria/genetics; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Bordetella pertussis/enzymology; Bordetella pertussis/genetics; Cytochrome c Group/biosynthesis; Cytochrome c Group/genetics; Female; Genome, Bacterial; Humans; Male; Oxygen/metabolism
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