PMID:11872734
| Citation |
Murphy, M, Schmid Nuoffer, S and Bickle, TA (2002) Lack of regulation of the modification-dependent restriction enzyme McrBC in Escherichia coli. J. Bacteriol. 184:1794-5 |
|---|---|
| Abstract |
Restriction alleviation (RA) by the type I restriction enzyme EcoKI is caused by treatments that damage DNA. RA is due to proteolysis of the EcoKI HsdR subunit by the ClpXP ATP-dependent protease. Here we show that the modification-dependent enzyme McrBC is not subject to RA, although it is moderately sensitive to ClpAP. |
| Links | |
| Keywords |
2-Aminopurine/pharmacology; Calcium-Binding Proteins/genetics; DNA Restriction Enzymes/genetics; DNA Restriction Enzymes/metabolism; Escherichia coli/enzymology; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Mutagenesis |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.