PMID:11837396
| Citation |
Saverino, D (2002) Beta-lactamase production by Escherichia coli under different growth conditions. New Microbiol. 25:89-91 |
|---|---|
| Abstract |
Facultative anaerobic bacteria, such as Escherichia coli, are more resistant to cephalosporin antibiotics during anaerobic growth. Strict anaerobic ambience reduces beta-lactamase production or the enzyme affinities for their substrates. A different balance between DNA gyrase and topoisomerase I activity, during aerobic and anaerobic growth condition, could be related to the bacteria behavior. |
| Links | |
| Keywords |
Cephalosporins/pharmacology; Escherichia coli/drug effects; Escherichia coli/enzymology; Escherichia coli/growth & development; beta-Lactam Resistance/genetics; beta-Lactamases/analysis; beta-Lactamases/biosynthesis |
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