PMID:11807064
| Citation |
Helling, RB (2002) Speed versus efficiency in microbial growth and the role of parallel pathways. J. Bacteriol. 184:1041-5 |
|---|---|
| Abstract |
Many microorganisms have sets of parallel pathways for ATP production in respiration and for ATP utilization in glutamate synthesis. The alternatives differ in efficiency of ATP production and utilization. The choice among these parallel pathways has been hypothesized to control the speed and efficiency of growth. Thus, the organism should be able to alleviate (or exaggerate) deficiency in one pathway by deleting another. I show here that in Escherichia coli the effect of lack of the glutamate-synthesizing enzyme glutamate dehydrogenase on glucose-limited growth is altered predictably by ndh, cyo, and cyd mutations affecting parallel pathways leading to ATP synthesis in respiration. |
| Links | |
| Keywords |
Culture Media; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Glutamate Dehydrogenase/genetics; Glutamate Dehydrogenase/metabolism; Mutagenesis; Time Factors |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.