PMID:11791232
| Citation |
Park, J and Bolser, D (2001) Conservation of protein interaction network in evolution. Genome Inform 12:135-40 |
|---|---|
| Abstract |
A functional analysis of protein fold interaction suggested that structural fold families have gradually acquired more diverse interacting partners while maintaining central biochemical interactions and functions. This means that the protein interaction network (map) maintains its robust architecture due to the functional constraints associated with the interactions. |
| Links | |
| Keywords |
Binding Sites; Computational Biology; Databases, Protein; Evolution, Molecular; Macromolecular Substances; Protein Binding; Protein Folding; Proteins/chemistry; Proteins/classification; Proteins/genetics; Proteins/metabolism |
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