PMID:11715047

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Citation

Peters, JE and Craig, NL (2001) Tn7: smarter than we thought. Nat. Rev. Mol. Cell Biol. 2:806-14

Abstract

A notable feature of transposable elements--segments of DNA that can move from one position to another in genomes--is that they are highly prevalent, despite the fact that their translocation can result in mutation. The bacterial transposon Tn7 uses an elaborate system of target-site selection pathways that favours the dispersal of Tn7 in diverse hosts as well as minimizing its negative effects.

Links

PubMed Online version:10.1038/35099006

Keywords

Adenosine Triphosphate/metabolism; Bacterial Proteins/physiology; DNA/chemistry; DNA Transposable Elements/genetics; DNA Transposable Elements/physiology; DNA-Binding Proteins/physiology; Escherichia coli Proteins; Models, Biological; Models, Genetic

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