PMID:11709172
| Citation |
Jensen, MO, Tajkhorshid, E and Schulten, K (2001) The mechanism of glycerol conduction in aquaglyceroporins. Structure 9:1083-93 |
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| Abstract |
The E. coli glycerol facilitator, GlpF, selectively conducts glycerol and water, excluding ions and charged solutes. The detailed mechanism of the glycerol conduction and its relationship to the characteristic secondary structure of aquaporins and to the NPA motifs in the center of the channel are unknown. |
| Links | |
| Keywords |
Amino Acid Motifs; Aquaporins/chemistry; Aquaporins/metabolism; Bacterial Outer Membrane Proteins/chemistry; Bacterial Outer Membrane Proteins/metabolism; Binding, Competitive; Biological Transport; Computer Simulation; Diffusion; Escherichia coli Proteins; Glycerol/metabolism; Hydrogen Bonding; Lipid Bilayers/metabolism; Models, Molecular; Motion; Protein Structure, Quaternary; Water/metabolism |
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