PMID:11683274

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Citation

Pfennig, PL and Flower, AM (2001) BipA is required for growth of Escherichia coi K12 at low temperature. Mol. Genet. Genomics 266:313-7

Abstract

The bipA gene encodes a ribosome-associated GTPase postulated to be involved in regulatory functions in enteropathogenic Escherichia coli. Previous studies demonstrated that BipA is tyrosine phosphorylated in EPEC strains, but not in E. coli strain K12. Results presented here indicate that BipA function is required at low temperatures in E. coli K12, suggesting a regulatory role independent of phosphorylation and of pathogenicity.

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Keywords

Cell Division/genetics; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli Proteins/genetics; Escherichia coli Proteins/physiology; GTP Phosphohydrolases/genetics; GTP Phosphohydrolases/physiology; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Mutation; Phenotype; Phosphoproteins; Plasmids/genetics; Repressor Proteins/genetics; Temperature; Transformation, Genetic

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