PMID:11591347
| Citation |
Martín, CS, Burnett, RM, de Haas, F, Heinkel, R, Rutten, T, Fuller, SD, Butcher, SJ and Bamford, DH (2001) Combined EM/X-ray imaging yields a quasi-atomic model of the adenovirus-related bacteriophage PRD1 and shows key capsid and membrane interactions. Structure 9:917-30 |
|---|---|
| Abstract |
The dsDNA bacteriophage PRD1 has a membrane inside its icosahedral capsid. While its large size (66 MDa) hinders the study of the complete virion at atomic resolution, a 1.65-A crystallographic structure of its major coat protein, P3, is available. Cryo-electron microscopy (cryo-EM) and three-dimensional reconstruction have shown the capsid at 20-28 A resolution. Striking architectural similarities between PRD1 and the mammalian adenovirus indicate a common ancestor. |
| Links | |
| Keywords |
Adenoviruses, Human/chemistry; Bacteriophage PRD1/chemistry; Bacteriophage PRD1/ultrastructure; Capsid/chemistry; Capsid/ultrastructure; Computer Simulation; Cryoelectron Microscopy/methods; Crystallography, X-Ray/methods; DNA, Viral/chemistry; DNA, Viral/ultrastructure; Image Enhancement/methods; Models, Molecular; Protein Conformation; Viral Envelope Proteins/chemistry; Viral Envelope Proteins/ultrastructure; Virion/chemistry; Virion/ultrastructure |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.