PMID:11544239
| Citation |
Genevaux, P, Schwager, F, Georgopoulos, C and Kelley, WL (2001) The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth. J. Bacteriol. 183:5747-50 |
|---|---|
| Abstract |
The DnaK chaperone of Escherichia coli is known to interact with the J domains of DnaJ, CbpA, and DjlA. By constructing multiple mutants, we found that the djlA gene was essential for bacterial growth above 37 degrees C in the absence of dnaJ. This essentiality depended upon the J domain of DjlA but not upon the normal membrane location of DjlA. |
| Links |
PubMed PMC95468 Online version:10.1128/JB.183.19.5747-5750.2001 |
| Keywords |
DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Escherichia coli Proteins; HSP40 Heat-Shock Proteins; Heat-Shock Proteins/genetics; Heat-Shock Proteins/metabolism; Hot Temperature; Mutation |
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