PMID:11525167
| Citation |
Xiang, S, Nichols, J, Rajagopalan, KV and Schindelin, H (2001) The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. Structure 9:299-310 |
|---|---|
| Abstract |
Molybdenum cofactor (Moco) biosynthesis is an evolutionarily conserved pathway present in archaea, eubacteria, and eukaryotes. In humans, genetic abnormalities in the biosynthetic pathway result in Moco deficiency, which is accompanied by severe neurological symptoms and death shortly after birth. The Escherichia coli MoeA and MogA proteins are involved in the final step of Moco biosynthesis: the incorporation of molybdenum into molybdopterin (MPT), the organic pyranopterin moiety of Moco. |
| Links | |
| Keywords |
Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins/chemistry; Carrier Proteins/metabolism; Conserved Sequence; Crystallography, X-Ray; Dimerization; Escherichia coli/enzymology; Escherichia coli Proteins/chemistry; Membrane Proteins/chemistry; Membrane Proteins/metabolism; Models, Molecular; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Sequence Alignment; Sulfurtransferases/chemistry |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.