PMID:11448770

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Citation

Argaman, L, Hershberg, R, Vogel, J, Bejerano, G, Wagner, EG, Margalit, H and Altuvia, S (2001) Novel small RNA-encoding genes in the intergenic regions of Escherichia coli. Curr. Biol. 11:941-50

Abstract

Small, untranslated RNA molecules were identified initially in bacteria, but examples can be found in all kingdoms of life. These RNAs carry out diverse functions, and many of them are regulators of gene expression. Genes encoding small, untranslated RNAs are difficult to detect experimentally or to predict by traditional sequence analysis approaches. Thus, in spite of the rising recognition that such RNAs may play key roles in bacterial physiology, many of the small RNAs known to date were discovered fortuitously.

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Keywords

Blotting, Northern; Chromosome Mapping; DNA, Intergenic; Escherichia coli/genetics; Oligodeoxyribonucleotides/genetics; Oligodeoxyribonucleotides/metabolism; Promoter Regions, Genetic/genetics; RNA, Bacterial/genetics; RNA, Untranslated/genetics; RNA, Untranslated/metabolism; Transcription, Genetic

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