PMID:11443233
| Citation |
Schuldiner, S, Granot, D, Mordoch, SS, Ninio, S, Rotem, D, Soskin, M, Tate, CG and Yerushalmi, H (2001) Small is mighty: EmrE, a multidrug transporter as an experimental paradigm. News Physiol. Sci. 16:130-4 |
|---|---|
| Abstract |
EmrE is a multidrug transporter from Escherichia coli that functions as a homooligomer and is unique in its small size. In each monomer there are four tightly packed transmembrane segments and one membrane-embedded charged residue. This residue provides the basis for the coupling mechanism as part of a binding site "time shared" by substrates and protons. |
| Links | |
| Keywords |
Amino Acid Sequence/genetics; Antiporters/genetics; Antiporters/physiology; Carrier Proteins/physiology; Escherichia coli Proteins; Membrane Proteins/genetics; Membrane Proteins/physiology; Molecular Sequence Data; Pharmaceutical Preparations/metabolism |
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