PMID:11386048
| Citation |
Tkachenko, AG and Nesterova, LIu [The role of putrescine in of oxidative stress defense genes expression regulation in Escherichia coli]. Mikrobiologiia 70:168-73 |
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| Abstract |
The role of putrescine in the adaptive response of Escherichia coli grown aerobically in synthetic M9 medium with glucose to the H2O2-induced oxidative stress was studied. Under oxidative stress, the expression of the single-copy reporter gene fusions oxyR::lacZ and katG::lacZ was found to undergo biphasic changes, which were most pronounced in glucose-starved E. coli cells. The concentration-dependent activating effect of putrescine on the expression of the oxyR regulon genes was maximum when the oxyR gene was inhibited by high concentrations of hydrogen peroxide. |
| Links | |
| Keywords |
Adaptation, Biological/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Gene Expression Regulation, Bacterial; Genes, Bacterial; Oxidative Stress/genetics; Putrescine/metabolism |
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