PMID:11371546

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Citation

Jung, K, Krabusch, M and Altendorf, K (2001) Cs(+) induces the kdp operon of Escherichia coli by lowering the intracellular K(+) concentration. J. Bacteriol. 183:3800-3

Abstract

Cs(+) was found to induce expression of the kdpFABC operon, encoding a high-affinity K(+) uptake system of Escherichia coli. Quantitative expression analyses at the transcriptional and translational levels reveal that CsCl causes much higher induction of kdpFABC than does NaCl. A decrease of the intracellular K(+) concentration is found in cells exposed to CsCl. The results indicate that kdpFABC expression is induced when the intracellular K(+) concentration is lowered. Moreover, the results imply that the signal transduction cascade mediated by KdpD and KdpE is able to integrate multiple signals.

Links

PubMed PMC95259 Online version:10.1128/JB.183.12.3800-3803.2001

Keywords

Adenosine Triphosphatases/genetics; Adenosine Triphosphatases/metabolism; Blotting, Northern; Blotting, Western; Carrier Proteins/genetics; Carrier Proteins/metabolism; Cation Transport Proteins; Cesium/metabolism; Cesium/pharmacology; Chlorides/metabolism; Chlorides/pharmacology; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Operon; Potassium/metabolism; RNA, Messenger/analysis; Water-Electrolyte Balance

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