PMID:11254968
| Citation |
Messer, W, Blaesing, F, Jakimowicz, D, Krause, M, Majka, J, Nardmann, J, Schaper, S, Seitz, H, Speck, C, Weigel, C, Wegrzyn, G, Welzeck, M and Zakrzewska-Czerwinska, J (2001) Bacterial replication initiator DnaA. Rules for DnaA binding and roles of DnaA in origin unwinding and helicase loading. Biochimie 83:5-12 |
|---|---|
| Abstract |
We review the processes leading to the structural modifications required for the initiation of replication in Escherichia coli, the conversion of the initial complex to the open complex, loading of helicase, and the assembly of two replication forks. Rules for the binding of DnaA to its binding sites are derived, and the properties of ATP-DnaA are described. We provide new data on cooperative interaction and dimerization of DnaA proteins of E. coli, Streptomyces and Thermus thermophilus, and on the stoichiometry of DnaA-oriC complexes of E. coli. |
| Links | |
| Keywords |
Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Base Sequence; DNA Helicases/genetics; DNA Helicases/metabolism; DNA Replication; DNA, Bacterial/genetics; DNA, Bacterial/metabolism; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Dimerization; DnaB Helicases; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Models, Molecular; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid/genetics; Replication Origin; Streptomyces/genetics; Streptomyces/metabolism; Thermus thermophilus/genetics; Thermus thermophilus/metabolism |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.