PMID:11159308

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Citation

Vasconcelos, AT, Maia, MA and de Almeida, DF (2000) Short interrupted palindromes on the extragenic DNA of Escherichia coli K-12, Haemophilus influenzae and Neisseria meningitidis. Bioinformatics 16:968-77

Abstract

The importance of the various kinds of repetitive nucleotide sequences for the workings of bacterial DNA has been widely recognized. This work is concerned with the distribution of a particular group of repetitive sequences, the short-sequenced interrupted extragenic palindromes, on the genetic maps of Escherichia coli K-12, Haemophilus influenzae Rd and Neisseria meningitidis Z2491 and MC58. A tool has been developed based upon a statistical hypothesis test taking into account the markovian structure of random sequences in order to determine the non-random character of extragenic palindromes.

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Keywords

Computational Biology; DNA, Bacterial/genetics; Escherichia coli/genetics; Genetic Techniques; Genome, Bacterial; Haemophilus influenzae/genetics; Neisseria meningitidis/genetics; Regression Analysis; Repetitive Sequences, Nucleic Acid

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