PMID:11157960
| Citation |
Nishino, K and Yamaguchi, A (2001) Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters. J. Bacteriol. 183:1455-8 |
|---|---|
| Abstract |
Overexpression of evgA, a response regulator of a two-component system, increased multidrug efflux in Escherichia coli. Since overexpression of the emrKY operon, which is controlled by evgAS, could account only for deoxycholate resistance, the evgAS locus apparently controls expression of at least one other multidrug efflux operon. |
| Links |
PubMed PMC95021 Online version:10.1128/JB.183.4.1455-1458.2001 |
| Keywords |
Amino Acid Sequence; Bacterial Proteins/biosynthesis; Biological Transport; Doxorubicin/metabolism; Drug Resistance, Microbial; Drug Resistance, Multiple/genetics; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data; P-Glycoprotein/genetics; P-Glycoprotein/metabolism; Rhodamines/metabolism; Signal Transduction; Transcription Factors/biosynthesis |
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