PMID:11042447
| Citation |
Unligil, UM and Rini, JM (2000) Glycosyltransferase structure and mechanism. Curr. Opin. Struct. Biol. 10:510-7 |
|---|---|
| Abstract |
The high-resolution X-ray crystal structures of a new form of bacteriophage T4 beta-glucosyltransferase, Escherichia coli MurG, Bacillus subtilis SpsA, bovine beta-1,4-galactosyltransferase 1 and rabbit N-acetylglucosaminyltransferase I have now been solved. These glycosyltransferase structures have provided the first detailed view of the structural basis of catalysis, as well as new insight into glycosyltransferase classification. |
| Links | |
| Keywords |
Animals; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Glycosyltransferases/chemistry; Glycosyltransferases/metabolism; Structure-Activity Relationship |
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